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Article

Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder.

Schizophrenia research - 1 Jul 2011

Abdolmaleky Hamid Mostafavi, Yaqubi Sahab, Papageorgis Panagiotis, Lambert Arthur W, Ozturk Sait, Sivaraman Vadivelu, Thiagalingam Sam

Abstract excerpt

INTRODUCTION: HTR2A gene has been the subject of numerous studies in psychiatric genetics because LSD, which resembles serotonin causes psychosis and atypical antipsychotic drugs target the HTR2A receptor. However, evidence for the role of HTR2A polymorphism(s) in schizophrenia (SCZ) and bipolar disorder (BD) has been elusive. We hypothesized that epigenetic dysregulation of HTR2A may be involved in...

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Identifiers

PMID: 21550210
DOI: 10.1016/j.schres.2011.04.007

Genes

HTR2A

Variants

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Source receipt: pubmed, retrieved 7 Sept 2026.

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