Article

Spatial Transcriptomics of Meningeal Inflammation Reveals Inflammatory Gene Signatures in Adjacent Brain Parenchyma

2023-06-06

Abstract excerpt

While modern high efficacy disease modifying therapies have revolutionized the treatment of relapsing-remitting multiple sclerosis, they are less effective at controlling progressive forms of the disease. Meningeal inflammation is a recognized risk factor for cortical grey matter pathology which can result in disabling symptoms such as cognitive impairment and depression, but the mechanisms linking meningeal infla...

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Literature Corpus work: 174cee88-b060-59a7-8c3e-6dc234d1b18f
DOI: 10.1101/2023.06.02.543421

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