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Article

Regulation of regulators: Role of the complement factor H-related proteins

1 Oct 2019

Abstract excerpt

The complement system, while being an essential and very efficient effector component of innate immunity, may cause damage to the host and result in various inflammatory, autoimmune and infectious diseases or cancer, when it is improperly activated or regulated. Factor H is a serum glycoprotein and the main regulator of the activity of the alternative complement pathway. Factor H, together with its splice variant...

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PMID: 31757608
DOI: 10.1016/j.smim.2019.101341

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