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Article

The complement factor H‐related proteins

26 Oct 2016

Abstract excerpt

The role of the complement factor H-related (FHR) proteins in homeostasis, pathogen defense, and autoimmune disease has recently attracted considerable interest. We highlight the exciting research that has contributed to our understanding of the FHR protein family. Unlike factor H, a potent negative regulator of complement C3 activation, the FHR proteins appear to promote C3 activation. These data have important...

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PMID: 27782332
DOI: 10.1111/imr.12477

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