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The Factor H protein family: The switchers of the complement alternative pathway

16 Nov 2022

Abstract excerpt

The factor H (FH) protein family is emerging as a complex network of proteins controlling the fate of the complement alternative pathway (AP) and dictating susceptibility to a wide range of diseases including infectious, inflammatory, autoimmune, and degenerative diseases and cancer. Composed, in man, of seven highly related proteins, FH, factor H-like 1, and 5 factor H-related proteins, some of the FH family...

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PMID: 36382387
DOI: 10.1111/imr.13166

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