Article
Super-enhancer-driven MLX mediates redox balance maintenance via SLC7A11 in osteosarcoma
2023-02-02
Abstract excerpt
<title>Abstract</title> <p>Osteosarcoma (OS) is a common type of bone tumor for which there has been limited therapeutic progress over the past three decades. The prevalence of transcriptional addiction in cancer cells emphasizes the biological significance and clinical relevance of super-enhancers. In this study, we found that Max-like protein X (MLX), a member of the Myc-MLX network, is driven by super-enhancer...
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Identifiers and source
- Literature Corpus work
- 16f10c84-1b57-5b0b-9bf9-9ac40cfceb61
- DOI
- 10.21203/rs.3.rs-2428040/v1