Article

FNDC5/irisin mediates hallmark brain alterations and cognitive impairment in acute intestinal injury/disease

2022-12-29

Abstract excerpt

Intestinal ischemia/reperfusion (II/R) injury is a highly-lethal clinical problem and communication between intestine-brain axis is vital. Unfortunately, the mechanisms underlying the changes are yet unclear. The present study aimed to determine whether FNDC5/irisin plays a role in the progressive cerebral injury and cognitive deficit following II/R and reveal the mechanisms. Herein, the II/R-treated FNDC5/irisin...

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Literature Corpus work: 1681e908-8208-549d-9924-c718e720d868
DOI: 10.21203/rs.3.rs-2382599/v1

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