Article

C5aR1 mediates progression of inflammatory responses in brain of rats after ischemia and reperfusion

2024-01-30

Abstract excerpt

C5a receptor 1 (C5aR1) can induce strong inflammatory response to injury. Targeting C5aR1 has emerged as a novel anti-inflammatory therapeutic method. However, the role of C5aR1 in cerebral ischemia and reperfusion (I/R) injury and the definitive mechanism have not been elucidated clearly. Here we determine whether C5aR1 signaling is essential to the development of post-ischemic inflammation and brain injury and w...

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Literature Corpus work: 84b2e0c4-4410-5fec-88fd-15247b008e8e
DOI: 10.22541/au.170665364.40923767/v1

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