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Article

Podoplanin influences the inflammatory phenotypes and mobility of microglia in traumatic brain injury.

Biochemical and biophysical research communications - 5 Mar 2020

Fei Maoxing, Wang Handong, Zhou Mengliang, Deng Chulei, Zhang Li, Han Yanling

Abstract excerpt

Traumatic brain injury (TBI) represents a major cause of death and disability worldwide. Exacerbated neuroinflammation following TBI causes secondary injury. Podoplanin (PDPN) is a small transmembrane mucin-like glycoprotein that promotes the inflammatory response in different tissues and cells. However, the contribution of PDPN to neuroinflammation and microglial activation is unknown. Here, we found that PDPN...

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Identifiers

PMID: 31866008
DOI: 10.1016/j.bbrc.2019.12.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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