Article

Targeted mRNP-phagy licenses translational activation during cellular metamorphosis

2025-05-06

Abstract excerpt

<title>Abstract</title> <p>Post-transcriptional mRNA storage and timed reactivation represent fundamental strategies for cellular adaptation, yet the mechanisms enabling selective mRNP remodeling remain enigmatic. Here we identify the MEX3D-HIP1 (MX-H) mRNP-phagy pathway and its executing organelle MXLV (MEX3D-associated lysosomal vesicle) as an evolutionarily conserved system for lysosome-mediated RBP clearance....

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Identifiers and source

Literature Corpus work: 16795885-f79e-5003-8535-23e7d2430b2d
DOI: 10.21203/rs.3.rs-6289188/v1

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