Article

A functional screen of translated pancreatic lncRNAs identifies a microprotein-independent role for <i>LINC00261</i> in endocrine cell differentiation

2020-04-29

Abstract excerpt

Long noncoding RNAs (lncRNAs) are a heterogenous group of RNAs, which can encode small proteins. The extent to which developmentally regulated lncRNAs are translated and whether the produced microproteins are relevant for human development is unknown. Here, we show that many lncRNAs in direct vicinity of lineage-determining transcription factors (TFs) are dynamically regulated, predominantly cytosolic, and highly...

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Literature Corpus work: f667ebde-65a1-5610-9b9a-972496f81a55
DOI: 10.1101/2020.04.28.062679

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A functional screen of translated pancreatic lncRNAs identifies a microprotein-independent role for <i>LINC00261</i> in endocrine cell differentiationDOI 10.1101/2020.04.28.062679Read

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