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Article

The influence of the phylogenetic inference pipeline on murine antibody repertoire sequencing data following viral infection

2020-03-22

Abstract excerpt

Understanding B cell evolution following vaccination or infection is crucial for instructing targeted immunotherapies when searching for potential therapeutic or virus-neutralizing antibodies. Antibody phylogenetics holds the potential to quantify both clonal selection and somatic hypermutation, two key players shaping B cell evolution. A wide range of bioinformatic pipelines and phylogenetic inference methods hav...

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Literature Corpus work
1658ab7c-6230-5b2e-90e8-e95f60c4d817
DOI
10.1101/2020.03.20.000521
Open publication

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The influence of the phylogenetic inference pipeline on murine antibody repertoire sequencing data following viral infectionDOI 10.1101/2020.03.20.000521
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