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Article

The Diversity and Molecular Evolution of B-Cell Receptors during Infection.

Molecular biology and evolution - 1 May 2016

Hoehn Kenneth B, Fowler Anna, Lunter Gerton, Pybus Oliver G

Abstract excerpt

B-cell receptors (BCRs) are membrane-bound immunoglobulins that recognize and bind foreign proteins (antigens). BCRs are formed through random somatic changes of germline DNA, creating a vast repertoire of unique sequences that enable individuals to recognize a diverse range of antigens. After encountering antigen for the first time, BCRs undergo a process of affinity maturation, whereby cycles of rapid somatic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26802217
DOI: 10.1093/molbev/msw015
PMCID: PMC4839220

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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