Article

SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns

2019-09-27

Abstract excerpt

Human pre-mRNA introns vary in size from under fifty to over a million nucleotides. We searched for essential factors involved in the splicing of human short introns by screening siRNAs against 154 human nuclear proteins. The splicing activity was assayed with a model HNRNPH1 pre-mRNA containing short 56-nucleotide intron. We identified a known alternative splicing regulator SPF45 (RBM17) as a constitutive splicin...

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Literature Corpus work: 1619757e-18dd-56bb-8066-bbde1f35be25
DOI: 10.1101/784868

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