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A Spatial Comparison of Molecular Features Associated with Resistance to Pembrolizumab in BCG Unresponsive Bladder Cancer

2023-11-30

Abstract excerpt

<h4>Background</h4> Intravenous immune checkpoint inhibition achieves a 40% three-month response in BCG-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS). Yet only half of early responders will continue to be disease free by 12 months, and resistance mechanisms are poorly defined. <h4>Objective</h4> We assessed the molecular features associated with response to immunotherapy in B...

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Literature Corpus work
1618b5d1-facd-5c7a-9983-a6da4fe0074e
DOI
10.1101/2023.11.28.23299093
Open publication

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A Spatial Comparison of Molecular Features Associated with Resistance to Pembrolizumab in BCG Unresponsive Bladder CancerDOI 10.1101/2023.11.28.23299093
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