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Digital spatial profiling of the microenvironment of muscle invasive bladder cancer

18 Jun 2024

Abstract excerpt

Muscle invasive bladder cancer (MIBC) is a molecularly diverse disease with varied clinical outcomes. Molecular studies typically employ bulk sequencing analysis, giving a transcriptomic snapshot of a section of the tumour. However, tumour tissues are not homogeneous, but are composed of distinct compartments such as the tumour and stroma. To investigate the molecular profiles of bladder cancer, whilst also...

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PMID: 38890455
DOI: 10.1038/s42003-024-06426-9

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