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Spatial biomarkers of response to neoadjuvant therapy in muscle-invasive bladder cancer: the DUTRENEO trial

2025-02-10

Abstract excerpt

Many studies have reported biomarkers predictive of response to immune checkpoint inhibitors (ICI) based on retrospective analyses. However, few clinical trials have tested their value prospectively. The DUTRENEO trial (EudraCT: 2017-002246-6) investigated whether an 18-gene Tumour Inflammation Signature (TIS) that can robustly identify patients who respond to ICI in multiple tumour types could stratify patients w...

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Literature Corpus work
09b39b60-7117-5aeb-aa32-cfb8b1c4d028
DOI
10.1101/2025.02.07.25321742
Open publication

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