Back to search

Article

Comprehensive Landscape of Non-muscle Invasive Bladder Cancer Tumour Microenvironment and Prognostic value of Cancer-Associated Myofibroblasts

2023-10-27

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Non-muscle-invasive bladder cancer (NMIBC) poses clinical challenges due to its high recurrence and progression rates. While Bacillus Calmette-Guérin (BCG) remains as the gold standard treatment for high-risk NMIBC, recent irruption of anti-PD-1/PD-L1 drugs claims for a comprehensive understanding of the tumour microenvironment (TME) of these tumors. <h4>METHODS</h4> The pr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4fa12438-cb6f-5269-a298-b2383067f59c
DOI
10.1101/2023.10.26.564112
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Comprehensive Landscape of Non-muscle Invasive Bladder Cancer Tumour Microenvironment and Prognostic value of Cancer-Associated MyofibroblastsDOI 10.1101/2023.10.26.564112
Cancer-associated Fibroblasts in Bladder Cancer: Origin, Biology, and Therapeutic OpportunitiesSemantic proximity
Tumour microenvironment (TME) characterization identified prognosis and immunotherapy response in muscle-invasive bladder cancer (MIBC).Semantic proximity
Single-Cell Proteomic Analysis Dissects the Complexity of Tumor Microenvironment in Muscle Invasive Bladder CancerSemantic proximity
Epithelial cell diversity and immune remodeling in bladder cancer progression: insights from single-cell transcriptomicsSemantic proximity
Multi-omics consensus ensemble refines the classification of muscle-invasive bladder cancer with stratified prognosis, tumour microenvironment and distinct sensitivity to frontline therapiesSemantic proximity
Single-cell and bulk RNA-sequence identified fibroblasts signature and CD8 + T-cell - fibroblast subtype predicting prognosis and immune therapeutic response of bladder cancer, based on machine learning: bioinformatics multi-omics studySemantic proximity
Increased stromal densities of B cells, CD103+ cells, and CD163+ M2-like macrophages associate with poor clinical outcomes in BCG treated non-muscle invasive bladder cancerSemantic proximity
Histopathologic, Molecular, and Clinical Profiling of Lymphoepithelioma-like Carcinoma of the Bladder.Semantic proximity
Hypoxia and epithelial to mesenchymal transition pathways are enriched in bladder tumor epithelium adjacent to tertiary lymphoid structuresSemantic proximity
Identification of a Novel Inflamed Tumor Microenvironment Signature as a Predictive Biomarker of Bacillus Calmette-Guérin Immunotherapy in Non-Muscle-Invasive Bladder Cancer.Semantic proximity
Development and validation of cancer-associated fibroblasts-related gene landscape in prognosis and immune microenvironment of bladder cancerSemantic proximity
In silico analysis and validation of the cancer-associated fibroblasts-related gene CAMK4 promotes bladder cancer progressionSemantic proximity
Select a neighboring publication to make it the new centre.