Article

<i>SOX2</i> dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the <i>FOSL2/IL6</i> axis

2022-06-09

Abstract excerpt

<h4>Background</h4> Inflammation is undoubtedly a hallmark of cancer development. Its maintenance within tumors and subsequent consequences on disease aggressiveness is less understood. <h4>Methods</h4> Multi-omic analyses of 27 (~ 5000 samples) entities from the TCGA, GEO and in-house data was performed to investigate the molecular determinant of tumor aggressiveness. Using molecular loss of function data, the...

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Literature Corpus work: 16037611-0ef9-539f-8dc7-598dcc59e937
DOI: 10.1101/2022.06.09.495487

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