Article

3D amplified single-cell RNA and protein imaging identifies oncogenic transcript subtypes in B cell acute lymphoblastic leukemia

2023-09-15

Abstract excerpt

Simultaneous in situ detection of transcript and protein markers at single-cell level is essential for gaining a better understanding of tumor heterogeneity and for predicting and monitoring treatment responses. However, the limited accessibility to advanced 3D imaging techniques has hindered its rapid implementation. Here, we present a 3D single-cell imaging technique, termed 3D digital rolling circle amplificati...

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Literature Corpus work: 15e0b0ed-cf19-59e3-8795-f00e96b975b7
DOI: 10.21203/rs.3.rs-3301570/v1

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