Article

Regulation of Kv2 channels by Kv9.1 variants

2024-11-29

Abstract excerpt

Kv2.1 channels have important conducting and nonconducting functions and are regulated by ‘silent’ Kv subunits. One of these is Kv9.1, which is co-expressed with Kv2 channels in sensory neurons, and a common allele which changes Ile489 to Val in human Kv9.1 promotes pain sensitivity. Here we examined the effects of Kv9.1 variants on Kv2 channels expressed in HeLa cells and primary hippocampal neurons. Both Kv9.1Il...

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Literature Corpus work: 15d62570-b15c-5797-81b6-d14fa834927a
DOI: 10.22541/au.173290530.04411602/v1

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