Article

A pain-reducing Kv6.4 variant spares other Kv6 channels, offering a target for uterine pain

2025-12-21

Abstract excerpt

Uterine pain conditions such as dysmenorrhea and endometriosis are highly prevalent, poorly managed, and associated with long-term impacts on women’s health. The identification of a rare KCNG4 variant (rs140124801; p.Val419Met) previously linked to reduced labor pain suggests Kv6.4 (encoded by KCNG4 ) may play a role in visceral nociception and offer a new target for non-opioid uterine pain relief. We analyzed...

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Literature Corpus work: acb11b66-d166-5ea5-9fb1-4d60e3605dbd
DOI: 10.64898/2025.12.18.692915

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