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Article

Differential modulation of Kv4 kinetics by KCHIP1 splice variants.

Molecular and cellular neurosciences - 1 Oct 2003

Van Hoorick Diane, Raes Adam, Keysers Wim, Mayeur Evy, Snyders Dirk J

Abstract excerpt

The beta-subunits of the KChIP family modulate properties and expression level of Kv4 channels. We report the cloning of the first splice variant of KChIP1 (KChIP1b) which contains an extra exon, rich in aromatic residues, in the amino terminus. Both splice variants interacted equally well with Kv4.2 subunits based on confocal imaging and upregulation of current density (more than five-fold). No effects on the...

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Identifiers

PMID: 14572458
DOI: 10.1016/s1044-7431(03)00174-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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