Article

Epistasis Detection using Model Based Multifactor Dimensionality Reduction in Structured Populations

2019-02-05

Abstract excerpt

In genome-wide association studies, the extent and impact of confounding due population structure have been well recognized. Inadequate handling of such confounding is likely to lead to spurious associations, hampering replication and the identification of causal variants. Several strategies have been developed for protecting associations against confounding, the most popular one is based on Principal Component An...

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Literature Corpus work: 15ce5e9f-fd9b-5f42-b991-3eabe8482da3
DOI: 10.1101/541946

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