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Article

Revealing the acute asthma ignorome: characterization and validation of uninvestigated gene networks

21 Apr 2016

Abstract excerpt

Systems biology provides opportunities to fully understand the genes and pathways in disease pathogenesis. We used literature knowledge and unbiased multiple data meta-analysis paradigms to analyze microarray datasets across different mouse strains and acute allergic asthma models. Our combined gene-driven and pathway-driven strategies generated a stringent signature list totaling 933 genes with 41% (440)...

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PMID: 27097888
DOI: 10.1038/srep24647

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