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Stress signalling and STAT1 activation characterize the keratinocytic gene expression pattern in Hidradenitis suppurativa

26 Jul 2022

Abstract excerpt

BACKGROUND: The pathogenetic factors generating the innate immune signal necessary for T-cell activation, initiation and chronification of Hidradenitis suppurativa (HS, also known as Acne inversa) are still poorly understood. Emerging evidence suggests that a defective keratinocyte function critically contributes to HS disease development and progression. OBJECTIVES: To elucidate the role of keratinocytes in HS...

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PMID: 35881108
DOI: 10.1111/jdv.18465

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