Article

A map of signaling responses in the human airway epithelium

2022-12-22

Abstract excerpt

Receptor-mediated signaling plays a central role in tissue regeneration, and it is dysregulated in disease. Here, we build a signaling–response map for a model regenerative human tissue: the airway epithelium. We analyzed the effect of 17 receptor-mediated signaling pathways on organotypic cultures to determine changes in abundance and phenotype of all epithelial cell types. This map recapitulates the gamut of kno...

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Literature Corpus work: 0fe57f8c-b9ef-5c75-8605-4f017e5dba05
DOI: 10.1101/2022.12.21.521460

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