Article

Repurposing public sarcoma multi-omics for neoantigen discovery

2026-02-22

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> : Soft tissue sarcomas, particularly Complex Karyotype Sarcomas (CKS), are characterized as "immunologically cold" malignancies driven by structural instability rather than a high tumor mutational burden (TMB). Public “legacy” cohorts are a useful resource to uncover immunotherapy biomarkers. This study used the Whole Exome Sequencing (WES) and RNA-sequencing...

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Literature Corpus work: 1548d6ec-cdb5-52f8-96fc-1ea341a6c8c0
DOI: 10.21203/rs.3.rs-8854019/v1

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