Article

Proteogenomic analysis reveals RNA as an important source for tumor-agnostic neoantigen identification correlating with T-cell infiltration

2022-09-18

Abstract excerpt

Systemic pan-tumor analyses may reveal the significance of common features implicated in cancer immunogenicity and patient survival. Here, we provide a comprehensive multi-omics data set for 32 patients across 25 tumor types by combining proteogenomics with phenotypic and functional analyses. By using an optimized computational approach, we discovered a large number of novel tumor-specific and tumor-associated ant...

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Literature Corpus work: fc2892b5-ea4c-5116-b0b2-b5213d63dd27
DOI: 10.1101/2022.09.17.508207

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