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Article

LINE-1 DNA methylation in response to aging and vitamin D

2020-05-03

Abstract excerpt

Retrotransposons are genetic elements capable of their own propagation and insertion into the human genome. Because of their mutagenic potential, retrotransposons are heavily suppressed by mechanisms including DNA methylation. Increased age is associated with decreasing DNA methylation of the LINE-1 retrotransposon and may partially explain the predisposition towards malignancy with advancing age. Vitamin D has be...

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Identifiers and source

Literature Corpus work
1533d4cf-ace9-569f-8a1c-5b6abc89653b
DOI
10.1101/2020.05.02.073551
Open publication

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LINE-1 DNA methylation in response to aging and vitamin DDOI 10.1101/2020.05.02.073551
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