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Micronutrient status and global DNA methylation in school-age children

6 Sept 2012

Abstract excerpt

Aberrations in global LINE-1 DNA methylation have been related to risk of cancer and cardiovascular disease. Micronutrients including methyl-donors and retinoids are involved in DNA methylation pathways. We investigated associations of micronutrient status and LINE-1 methylation in a cross-sectional study of school-age children from Bogotá, Colombia. Methylation of LINE-1 repetitive elements was quantified in 568...

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PMID: 22918385
DOI: 10.4161/epi.21915

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