Article

Detection of Somatic Copy Number Deletion of the <i>CDKN2A</i> Gene by Quantitative Multiplex PCR for Clinical Practice

2021-09-24

Abstract excerpt

<h4>Background</h4> While the amplification of oncogenes (such as EGFR , c- ERBB2 , c- MYC , and c- MET ) are increasingly driving decision-making for precise cancer treatments, a feasible method to detect somatic copy number deletion (SCND) of tumor suppressor genes is still absent to date. <h4>Methods</h4> The genomic coordinates of gene deletion fragments were analyzed using the Catalogue Of Somatic Mutation In...

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Literature Corpus work: 152be092-21cb-5a0c-ac6f-a408e9927874
DOI: 10.1101/2021.09.16.21263412

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