Article
Telomere shortening produces an inflammatory environment that promotes tumor invasiveness in zebrafish
2019-11-15
Abstract excerpt
Cancer incidence increases exponentially with age, when human telomeres are shorter. Similarly, telomerase mutant zebrafish ( tert ) have premature short telomeres and anticipate cancer incidence to younger ages. However, because short telomeres constitute a road block to cell proliferation, telomere shortening is currently viewed as a tumor suppressor mechanism and should protect from cancer. This conundrum is n...
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Identifiers and source
- Literature Corpus work
- 14dc80ae-2ae0-5cf9-ad19-f251af0bc862
- DOI
- 10.1101/844084