Back to search

Article

A wavelet-based approach generates quantitative, scale-free and hierarchical descriptions of 3D genome structures and new biological insights

2024-07-16

Abstract excerpt

<h4>ABSTRACT</h4> Eukaryotes fold their genomes within nuclei in three-dimensional space, with coordinated multiscale structures including loops, topologically associating domains (TADs), and higher-order chromosome territories. This 3D organization plays essential roles in gene regulation and development, responses to physiological stress, and disease. However, current methodologies to infer these 3D structures...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
14c69071-f58e-5e04-989c-bea833a2b27f
DOI
10.1101/2024.07.12.603291
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A wavelet-based approach generates quantitative, scale-free and hierarchical descriptions of 3D genome structures and new biological insightsDOI 10.1101/2024.07.12.603291
Dynamic Network Analysis of the 4D NucleomeSemantic proximity
Examining dynamics of three-dimensional genome organization with multi-task matrix factorizationSemantic proximity
VECTOR: A Framework to Identify and Quantify Structural Changes in Chromatin using Hi-C DataSemantic proximity
Sequence-based modeling of genome 3D architecture from kilobase to chromosome-scaleSemantic proximity
TAD Cliques Predict Key Features of Chromatin OrganizationSemantic proximity
Three-dimensional chromatin organization in cardiac development and disease.Semantic proximity
chromperiod: a Python package for detecting periodic chromatin organization from consecutive accessibility peaksSemantic proximity
A scaling law of periodic radial geometry organises eukaryotic chromosomesSemantic proximity
DeDoc2 identifies and characterizes the hierarchy and dynamics of chromatin TAD-like domains in the single cellsSemantic proximity
DeDoc2 identifies and characterizes the hierarchy and dynamics of chromatin TAD-like domains in the single cellsSemantic proximity
chromperiod: a Python package for detecting periodic chromatin organization from consecutive accessibility peaksSemantic proximity
TAD cliques predict key features of chromatin organizationSemantic proximity
Select a neighboring publication to make it the new centre.