Article

Organellomics: AI-driven deep organellar phenotyping reveals novel ALS mechanisms in human neurons

2024-01-31

Abstract excerpt

Systematic assessment of organelle architectures, termed the organellome , offers valuable insights into cellular states and pathomechanisms, but remains largely uncharted. Here, we present a deep phenotypic learning based on vision transformers, resulting in the Neuronal Organellomics Vision Atlas (NOVA) model that studies confocal images of more than 30 markers of distinct membrane-bound and membraneless organe...

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Literature Corpus work: cedb4938-42bd-52ee-8260-f786ba9cf0c5
DOI: 10.1101/2024.01.31.572110

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