Article

The impact of genetic background and sex on the phenotype of IL-23 induced murine arthritis

2021-02-03

Abstract excerpt

<h4>Background</h4> Overexpression of IL-23 in adult mice by means of hydrodynamic tail vein injection of IL-23 minicircles has been reported to result in spondyloarthritis-like disease. The impact of genetic background and sex on the disease phenotype in this model has not been investigated. <h4>Methods</h4> We compared male B10.RIII mice with male C57BL/6 mice, and male with female B10.RIII mice after hydrodyn...

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Literature Corpus work: 148de636-32ec-55bf-bba1-f19c8925e0d2
DOI: 10.1101/2021.02.03.429523

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