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Article

The impact of genetic background and sex on the phenotype of IL-23 induced murine spondyloarthritis.

PloS one - 1 Jan 2021

Haley Emma K, Matmusaev Mederbek, Hossain Imtiyaz N, Davin Sean, Martin Tammy M, Ermann Joerg

Abstract excerpt

BACKGROUND: Overexpression of IL-23 in adult mice by means of hydrodynamic tail vein injection of IL-23 minicircles has been reported to result in spondyloarthritis-like disease. The impact of genetic background and sex on the disease phenotype in this model has not been investigated. METHODS: We compared male B10.RIII mice with male C57BL/6 mice, and male with female B10.RIII mice after hydrodynamic injection of...

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Identifiers

PMID: 33983951
DOI: 10.1371/journal.pone.0247149
PMCID: PMC8118278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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