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Article

Illuminating the impact of γδ T cells in man and mice in spondylarthritides.

European journal of immunology - 1 Oct 2024

Meyer Anja

Abstract excerpt

Spondylarthritides (SpA) are a group of autoinflammatory diseases affecting the spine, peripheral joints, and entheses, including axial spondyloarthritis (axSpA) and psoriatic arthritis. AxSpA has a multifactorial etiology that involves genetic predispositions, such as HLA-B27 and IL-23R. Although HLA-B27 is strongly associated with axSpA, its role remains unclear. GWAS studies have demonstrated that genetic...

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PMID: 39077953
DOI: 10.1002/eji.202451071

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