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Article

A Novel human IL-23A Overexpressing Mouse Model of Systemic Lupus Erythematosus

2023-11-10

Abstract excerpt

<h4>Objective</h4> Interleukin-23 (IL-23) is a crucial cytokine implicated in chronic inflammation and autoimmunity, associated with various diseases like psoriasis, psoriatic arthritis, and systemic lupus erythematosus (SLE). This study aimed to create and characterize a transgenic mouse model (TghIL23A) overexpressing human IL23A, providing a valuable tool for investigating the pathogenic role of hIL23A and eva...

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Literature Corpus work
bd7d128a-7379-5b9e-b945-c1273591f60a
DOI
10.1101/2023.11.08.566163
Open publication

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A Novel human IL-23A Overexpressing Mouse Model of Systemic Lupus ErythematosusDOI 10.1101/2023.11.08.566163
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