Article

GALA: a computational framework for de novo chromosome-by-chromosome assembly with long reads

2022-03-02

Abstract excerpt

<title>Abstract</title> <p>High-quality genome assembly has wide applications in genetics and medical studies. However, it is still very challenging to achieve gap-free chromosome-scale assemblies using current workflows for long-read platforms. Here we report on GALA (Gap-free long-read assembler), a computational framework for de novo chromosome-by-chromosome assembly implemented through a multi-layer graph tha...

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Literature Corpus work: 147989ef-ad9a-50a2-9562-c94c9e65decc
DOI: 10.21203/rs.3.rs-1339386/v1

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