Article

GPatch enables chromosome-scale, gap-free pseudoassemblies from fragmented draft genomes

2025-05-27

Abstract excerpt

Recent advancements in sequencing technologies have yielded numerous long-read draft genomes, promising to enhance understanding of genomic variation. However, draft genomes are typically highly fragmented, posing challenges for functional genomics. We introduce GPatch, a tool that constructs chromosome-scale pseudoassemblies from fragmented drafts using alignments to a reference assembly. GPatch produces complete...

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Identifiers and source

Literature Corpus work: 11116ddf-364b-5caa-b649-0a25d6fc24cd
DOI: 10.1101/2025.05.22.655567

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