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GABOLA: A Reliable Gap-Filling Strategy for <i>de novo</i> Chromosome-Level Assembly

2021-09-08

Abstract excerpt

We propose a novel method, GABOLA, which utilizes long-range genomic information provided by accurate linked short reads jointly with long reads to improve the integrity and resolution of whole genome assemblies especially in complex genetic regions. We validated GABOLA on human and Japanese eel genomes. On the two human samples, we filled in more bases spanning 23.3Mbp and 46.2Mbp than Supernova assembler, coveri...

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Identifiers and source

Literature Corpus work
407e7475-95e1-506e-952a-037ef2b8a0dd
DOI
10.1101/2021.09.07.459217
Open publication

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GABOLA: A Reliable Gap-Filling Strategy for <i>de novo</i> Chromosome-Level AssemblyDOI 10.1101/2021.09.07.459217
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