Article

NSrp70 suppresses metastasis in triple-negative breast cancer by modulating Numb/TβR1/EMT axis

2021-03-18

Abstract excerpt

Metastasis is a major cause of death in individuals suffering from triple-negative breast cancer. Alternative splicing of mRNA precursor allows cancer cells to create different protein isoforms which may promote metastasis. Quantitative proteomic analysis of primary and metastatic breast cancer cells revealed that nuclear speckle-related protein 70 (NSrp70) was significantly downregulated in highly metastatic cell...

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Literature Corpus work: 144f7350-365e-5d09-b63a-2a89abcbc380
DOI: 10.21203/rs.3.rs-311222/v1

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