Article

LSM4 drives the progression of triple-negative breast cancer through alternative splicing

2026-04-08

Abstract excerpt

<title>Abstract</title> <p>Triple-negative breast cancer (TNBC) remains a therapeutic challenge due to its aggressive nature and limited treatment options. Through integrated genomic and proteomic profiling, we identified the RNA-binding protein LSM4 as a key driver of TNBC progression. LSM4 was significantly upregulated in TNBC tissues and showed progressively increasing expression from normal breast epithelial...

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Literature Corpus work: 099d9fe0-c97b-5570-b8e0-50be3acabed5
DOI: 10.21203/rs.3.rs-9275393/v1

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