Article
NSrp70 is a novel nuclear speckle-related protein that modulates alternative pre-mRNA splicing in vivo.
Nucleic acids research - 1 May 2011
Kim Young-Dae, Lee Jung-Yoon, Oh Kyu-Man, Araki Masatake, Araki Kimi, Yamamura Ken-ichi, Jun Chang-Duk
Abstract excerpt
Nuclear speckles are known to be the storage sites of mRNA splicing regulators. We report here the identification and characterization of a novel speckle protein, referred to as NSrp70, based on its subcellular localization and apparent molecular weight. This protein was first identified as CCDC55 by the National Institutes of Health Mammalian Gene Collection, although its function has not been assigned. NSrp70...
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