Article
Control of lineage-specific gene expression by functionalized gRNA barcodes
2017-08-21
Abstract excerpt
Lineage tracking delivers essential quantitative insight into dynamic, probabilistic cellular processes, such as somatic tumor evolution and differentiation. Methods for high diversity lineage quantitation rely on sequencing the population of DNA barcodes. However, molecular analysis of specific individual lineages is not possible with this approach. To address this challenge, we developed a functionalized lineage...
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Identifiers and source
- Literature Corpus work
- 144cc277-85d7-5ffd-ae25-f25dcf683007
- DOI
- 10.1101/178897