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Article

Endogenous CRISPR/Cas9 arrays for scalable whole-organism lineage tracing.

Development (Cambridge, England) - 12 May 2020

Cotterell James, Vila-Cejudo Marta, Batlle-Morera Laura, Sharpe James

Abstract excerpt

The past decade has seen a renewed appreciation of the central importance of cellular lineages to many questions in biology (especially organogenesis, stem cells and tumor biology). This has been driven in part by a renaissance in genetic clonal-labeling techniques. Recent approaches are based on accelerated mutation of DNA sequences, which can then be sequenced from individual cells to re-create a 'phylogenetic'...

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PMID: 32398353
DOI: 10.1242/dev.184481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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