Article

Glioma Cells Achieve Malignant Progression by Fusion with Macrophages to Gain High SLC7A5 Expression

2024-05-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Glioma is the most prevalent primary tumor of the central nervous system (CNS) in adults, and its high proliferative and invasive capacities are typically associated with a poor prognosis. Cell fusions are a crucial phenomenon in both physiological and pathological processes. Within tumors, tumor cells can acquire diverse gene expression profiles and undergo mali...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 144971b5-c910-5648-b641-7af2afef14e1
DOI: 10.21203/rs.3.rs-4281982/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Glioma Cells Achieve Malignant Progression by Fusion with Macrophages to Gain High SLC7A5 ExpressionDOI 10.21203/rs.3.rs-4281982/v1Read

Cancer cell-macrophage fusion increases tumor cell heterogeneity and reshapes their microenvironmentSemantic proximity Read

The impact and outcomes of cancer-macrophage fusionSemantic proximity Read

Hypoxia-induced polypoid giant cancer cells in glioma promote the transformation of tumor-associated macrophages to a tumor-supportive phenotype.Semantic proximity Read

Single-Cell Transcriptomic Analysis Revealed a Critical Role of SPP1/CD44-Mediated Crosstalk Between Macrophages and Cancer Cells in GliomaSemantic proximity Read

Identification of the clinical and genetic characteristics of gliomas with gene fusions by integrated genomic and transcriptomic analysisSemantic proximity Read

Tumor-Cell–Macrophage Fusion Cells as Liquid Biomarkers and Tumor Enhancers in CancerSemantic proximity Read

Fusion of Invasive Tumor Cells with Infiltrating Macrophages Fuels Epithelial-Mesenchymal Transition and Adaptive Immune EvasionSemantic proximity Read

Phagocytosis of Glioma Cells Enhances the Immunosuppressive Phenotype of Bone Marrow-Derived Macrophages.Semantic proximity Read

Cancer Cell Fusion and Post-Hybrid Selection Process (PHSP)Semantic proximity Read

Epithelial-mesenchymal transition is the main way in which glioma-associated microglia/macrophages promote glioma progressionSemantic proximity Read

Gene Fusion in Malignant Glioma: An Emerging Target for Next-Generation Personalized TreatmentSemantic proximity Read

You complete me: tumor cell-myeloid cell nuclear fusion as a facilitator of organ-specific metastasisSemantic proximity Read