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Article

Gene Fusion in Malignant Glioma: An Emerging Target for Next-Generation Personalized Treatment

20 Mar 2018

Abstract excerpt

Malignant gliomas are heterogeneous diseases in genetic basis. The development of sequencing techniques has identified many gene rearrangements encoding novel oncogenic fusions in malignant glioma to date. Understanding the gene fusions and how they regulate cellular processes in different subtypes of glioma will shed light on genomic diagnostic approaches for personalized treatment. By now, studies of gene...

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PMID: 29571074
DOI: 10.1016/j.tranon.2018.02.020

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