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The impact and outcomes of cancer-macrophage fusion

1 Jun 2023

Abstract excerpt

BACKGROUND: Cancer's hallmark feature is its ability to evolve, leading to metastasis and recurrence. Although genetic mutations and epigenetic changes have been implicated, they don't fully explain the leukocytic traits that many cancers develop. Cell fusion between cancer and somatic cells, particularly macrophages, has been suggested as an alternative pathway for cancer cells to obtain new traits by acquiring...

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PMID: 37264310
DOI: 10.1186/s12885-023-10961-9

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